Treatment of metastatic non-small cell lung cancer : a systematic review of comparative effectiveness and cost-effectiveness
Title
Treatment of metastatic non-small cell lung cancer : a systematic review of comparative effectiveness and cost-effectiveness / Paul G. Shekelle [and three others].
Published by
Washington, DC : Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service, 2012.
1 online resource (iv, 82 pages) : one illustration
Summary
Lung cancer is the leading cause of cancer death in both men and women in the United States, and male Veterans seeking care at VA hospitals have a much higher age-specific incidence of lung cancer than males in the general population. The personal and economic significance of lung cancer has led to a vast research endeavor to try and identify new and more effective treatments. Most patients with lung cancer are diagnosed when the cancer is already advanced (stage IIIB or IV), and they are no longer candidates for surgical resection. Small cell lung cancer and non-small cell lung cancer (NSCLC) are different diseases in terms of treatment. Until recently, all therapies for advanced NSCLC were based on their cytotoxic properties. In the last few years, several novel agents aimed at specific molecular targets have been developed. This review was requested to evaluate the current evidence on the effectiveness and cost-effectiveness of treatments for advanced lung cancer.
Includes bibliographical references (pages 54-70).
Funding (note)
Prepared for: Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service, Washington, DC 20420. Prepared by: Evidence-based Synthesis Program (ESP) Center, West Los Angeles VA Medical Center, Los Angeles, CA, Paul G. Shekelle, M.D., Ph. D., Director.
VA-ESP
Source of description (note)
Description based on online resource; title from PDF cover (VA, viewed April 22, 2021).
Author
Shekelle, Paul G., author.
Title
Treatment of metastatic non-small cell lung cancer : a systematic review of comparative effectiveness and cost-effectiveness / Paul G. Shekelle [and three others].
Publisher
Washington, DC : Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service, 2012.
Type of content
text
Type of medium
computer
Type of carrier
online resource
Bibliography
Includes bibliographical references (pages 54-70).
Funding
Prepared for: Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service, Washington, DC 20420. Prepared by: Evidence-based Synthesis Program (ESP) Center, West Los Angeles VA Medical Center, Los Angeles, CA, Paul G. Shekelle, M.D., Ph. D., Director.