Research Catalog

Details

Additional authors

1. Mitelman, Felix.

Description

1. x, 536 pages : illustrations; 24 cm

Summary

1. Over the past decade, cancer cytogenetics has become widely recognized both as a basic research tool for investigations of tumor biology and a clinical methodology providing vital insights into cancer development and progression.
2. Written by two leading experts, Cancer Cytogenetics, Second Edition provides an authoritative description of neoplastic processes at the chromosomal level of genomic organization. The book opens with a summary of cytogenetic methods and terminology, then reviews the key aspects of chromosomal abnormalities in cancer. The remainder of the book is devoted to the karyotypic and molecular genetic characteristics of specific neoplastic disorders and their clinical implications.
3. Included in these sections are eleven entirely new chapters focusing on different types of non-hematologic neoplasms. This extensive expansion from the single-chapter coverage of the first edition was necessitated by a veritable explosion of knowledge in the field of solid tumor cytogenetics.
4. . Specific topics in the Second Edition include: acute and chronic myeloproliferative disorders; myelodysplastic syndromes; acute and chronic lymphoproliferative disorders; malignant lymphomas; and solid tumors of the respiratory, digestive, and urinary tracts; breast, genital, endocrine, and nervous systems; eye, skin, and bone; and soft tissue.
5. This Second Edition of Cancer Cytogenetics is a valuable resource for researchers in a wide range of fields, including cytogenetics, medical and molecular genetics, cellular and molecular biology, oncology, and hematology. With its complete coverage of the cytogenetic mechanisms underlying neoplasia, this text will also be an indispensable reference for all clinicians involved in the diagnosis and treatment of cancer patients.

Subject

1. Cancer > Genetic aspects
2. Cytogenetics
3. Neoplasms > genetics
4. Cytogenetics > methods
5. Chromosome Aberrations > genetics

Contents

1. Ch. 1. A New Approach to an Old Problem -- Ch. 2. Cytogenetic Methods and Terminology -- Ch. 3. Nonrandom Chromosome Abnormalities in Cancer - An Overview -- Ch. 4. Chronic Myeloid Leukemia -- Ch. 5. Acute Myeloid Leukemia -- Ch. 6. Myelodysplastic Syndromes -- Ch. 7. Chronic Myeloproliferative Disorders -- Ch. 8. Acute Lymphoblastic Leukemia -- Ch. 9. Chronic Lymphoproliferative Disorders -- Ch. 10. Malignant Lymphomas -- Ch. 11. Tumors of the Respiratory Tract -- Ch. 12. Tumors of the Digestive Tract -- Ch. 13. Tumors of the Urinary Tract -- Ch. 14. Tumors of the Breast -- Ch. 15. Tumors of the Female Genital Organs -- Ch. 16. Tumors of the Male Genital Organs -- Ch. 17. Tumors of the Endocrine Glands -- Ch. 18. Tumors of the Nervous System -- Ch. 19. Tumors of the Eye -- Ch. 20. Tumors of the Skin -- Ch. 21. Tumors of Bone and Soft Tissue.

Owning institution

1. Columbia University Libraries

Bibliography (note)

1. Includes bibliographical references and index.