Research Catalog

Molecular mechanisms of muscarinic acetylcholine receptor function

Title
  1. Molecular mechanisms of muscarinic acetylcholine receptor function / Jürgen Wess.
Published by
  1. Austin, Tex. : R.G. Landes Co., [1995], ©1995.
Author
  1. Wess, Jürgen, 1958-

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Details

Description
  1. 272 pages : illustrations; 27 cm.
Series statement
  1. Molecular biology intelligence unit
Uniform title
  1. Molecular biology intelligence unit.
Subject
  1. Cellular signal transduction
  2. G proteins
  3. Muscarinic receptors
Contents
  1. 1. Mutational Analysis of Muscarinic Receptors: Structural Basis of Ligand Binding and G Protein Recognition / Jurgen Wess, Jie Liu, Klaus Bluml, June Yun, Torsten Schoneberg and Nathalie Blin -- 2. Binding-Site Modeling of the Muscarinic m1 Receptor - Molecular Interactions with Agonists and Antagonists / Gunnar Nordvall and Uli Hacksell -- 3. Signal Transduction Pathways Activated by Muscarinic Receptor Subtypes / Christian C. Felder -- 4. Pharmacological Analysis of Muscarinic Receptor-Mediated Inhibition of Adenylate Cyclase and Stimulation of Phosphoinositide Hydrolysis / Frederick J. Ehlert and Henry I. Yamamura -- 5. Acute Regulation of Muscarinic Receptor-Mediated Stimulation of Phosphoinositide Hydrolysis / G. B. Willars and S. R. Nahorski -- 6. Cardiac Muscarinic Cholinergic Receptor Signaling: Phospholipase C Activation, Kinase Cascades, and Gene Expression / M. Teresa Ramirez and Joan Heller Brown --
  2. 7. Proliferative Signaling Through Muscarinic Receptors: A Model for Receptors Coupled to Heterotrimeric G Proteins / J. Silvio Gutkind, Piero Crespo, Omar A. Coso, Gilda Kalinec and Ningzhi Xu -- 8. Dual Modulation of a Delayed Rectifier Potassium Channel by G Protein Coupled Receptors / Anthony D. Morielli, Xin-Yun Huang and Ernest G. Peralta -- 9. Coupling of Muscarinic Acetylcholine Receptors to Neutral Ion Channels: Closure of K+ Channels / D. A. Brown, N. J. Buckley, M. P. Caulfield, S. M. Duffy, S. Jones, J. A. Lamas, S. J. Marsh, J. Robbins and A. A. Selyanko -- 10. Structural Basis of Muscarinic Receptor Sequestration and Down-Regulation / Melinda S. Shockley, Jelveh Lameh and Wolfgang Sadee -- 11. Regulation of Expression and Function of Muscarinic Receptors / Phyllis S. Goldman and Neil M. Nathanson -- 12. Role of Protein Phosphorylation in the Desensitization of Muscarinic Receptors / Shubhik K. DebBurman and M. Marlene Hosey --
  3. 13. Phosphorylation and Sequestration of Muscarinic Receptors / Tatsuya Haga, Kazuko Haga, Kimihiko Kameyama and Hirofumi Tsuga -- 14. Regulation of Muscarinic Receptor Expression by Changes in Receptor mRNA Stability / Norman H. Lee and Claire M. Fraser.
Owning institution
  1. Columbia University Libraries
Bibliography (note)
  1. Includes bibliographical references and index.