Principles of molecular virology

Title
  1. Principles of molecular virology / Alan J. Cann.
Published by
  1. San Diego : Academic Press, 1997.
Author
  1. Cann, Alan.

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StatusFormatTextAccessRequest in advanceCall numberQR389 .C36 1997Item locationOff-site

Details

Description
  1. xii, 310 pages : illustrations; 25 cm
Subject
  1. Genome, Viral
  2. Virus Physiological Phenomena
  3. Virus Diseases
  4. Molecular virology
  5. Gene Expression Regulation, Viral
  6. Virus Replication
Contents
  1. Ch. 1. Introduction. Viruses are distinct from 'living' organisms. The origins of virology. Living host systems. Cell culture methods. Serological/immunological methods. Ultrastructural studies. 'Molecular biology' -- Ch. 2. Particles. The function and formation of virus particles. Capsid symmetry and virus architecture. Enveloped viruses. Complex structures. Protein-nucleic acid interactions and genome packaging. Virus receptors - recognition and binding. Other interactions of the virus capsid with the host cell -- Ch. 3. Genomes. The structure and complexity of virus genomes. Molecular genetics. Virus genetics. 'Large' DNA genomes. 'Small' DNA genomes. Positive-strand RNA viruses. Negative-strand RNA viruses. Segmented and multipartite virus genomes. Reverse transcription and transposition. Evolution and epidemiology -- Ch. 4. Replication. Overview of virus replication. Investigation of virus replication. The replication cycle -- Ch. 5. Expression.
  2. Expression of genetic information. Control of prokaryote gene expression. Control of expression in bacteriophage [lambda]. Control of eukaryote gene expression. Genome coding strategies. Transcriptional control of expression. Post-transcriptional control of expression -- Ch. 6. Infection. Virus infections of plants. Immune responses to virus infections in animals. Virus-host interactions. The course of virus infections. Prevention and therapy of virus infection. Virus vectors and gene therapy. Chemotherapy of virus infections -- Ch. 7. Pathogenesis. Mechanisms of cellular injury. Viruses and immunodeficiency. Virus-related diseases. Cellular transformation by viruses. Viruses and cancer. New and emergent viruses -- Ch. 8. Novel infectious agents: genomes without viruses, viruses without genomes. Satellites and viroids. Prions. App. 1. Classification of subcellular infectious agents.
Owning institution
  1. Columbia University Libraries
Bibliography (note)
  1. Includes bibliographical references and index.