Research Catalog

Details

Additional authors

1. George, Susan R.
2. O'Dowd, Brian Francis, 1950-

Description

1. xviii, 329 pages : illustrations; 26 cm.

Summary

1. "G Protein-Coupled Receptor-Protein Interactions will not only prove invaluable to scientists and academicians researching GPCR signal transduction systems, but will appeal to pharmaceutical industry professionals, since the GPCR family of proteins are targeted by over half of currently used therapeutic agents."--BOOK JACKET.

Series statement

1. Receptor biochemistry and methodology

Uniform title

1. Receptor biochemistry and methodology (Unnumbered)

Subject

1. G proteins
2. Cell receptors
3. Cellular signal transduction
4. GTP-Binding Proteins
5. Receptors, Cell Surface
6. Adaptor Proteins, Signal Transducing

Contents

1. Foreword / Robert J. Lefkowitz -- Series preface / David R. Sibley -- Preface / Susan R. George and Brian F. O'Dowd -- 1. Purification of the G protein-coupled receptor rhodopsin for structural studies / David Salom, Ning Li, Li Zhu, Izabela Sokal and Krzysztof Palczewski -- 2. Cooperativity in ligand binding to deduce receptor-receptor interaction / Meritxell Vivo and Philip G. Strange -- 3. Analysis of receptor-receptor interactions using time-resolved fluorescence resonance energy transfer / Douglas Ramsay and Graeme Milligan -- 4. Real-time imaging of GPCR-mediated arrestin translocation as a strategy to evaluate receptor-protein interactions / Robert H. Oakley, Larry S. Barak and Marc G. Caron -- 5. Localization of G protein-coupled receptors and interacting proteins in membrane microdomains / K. Saidas Nair, Vijaya Narayanan and Vladlen Z. Slepak -- 6. Identification of peptide ligand-binding domains within G protein-coupled receptors using photoaffinity labeling / Maoqing Dong and Laurence J. Miller -- 7. Analysis in real-time of the assembly and disassembly of soluble G protein-coupled-receptor-G protein complexes / Sean M. Biggs, Peter I. Simons, Anna Waller, Terry Foutz, Tione Buranda, Eric R. Prossnitz and Larry A. Sklar -- 8. Approaches to studying membrane protein oligomerization : use of cysteine crosslinking strategies to analyze receptor-receptor interactions / Jonathan A. Javitch, Wen Guo and Marisa E. Ring -- 9. Co-immunoprecipitation as a strategy to evaluate receptor-receptor or receptor-protein interactions / Randy A. Hall -- 10. Use of MALDI-TOF and mass spectrometry in the evaluation of receptor-protein interactions / John R. Raymond, Henry Ayiku, Justin Turner, Andrew Gelasco and John M. Arthur -- 11. Use of the yeast two-hybrid system to detect receptor-protein interactions / Ridwan Lin, Nadine Kabbani, Alicia Binda, Victor Canfield and Robert Levenson -- 12. GST fusion protein and pull-down strategies to evaluate receptor-receptor or receptor-protein interactions / Frank J. S. Lee and Fang Liu -- 13. G protein fusion to monitor integral membrane protein-protein interactions / Henrik Dohlman and Kathleen Ehrhard -- 14. Enzyme-linked immunosorbent assays as tools in studying interactions of G protein-coupled receptors / Torsten Schoneberg, Katrin Sangkuhl, Holger Rompler and Angela Schulz -- 15. Electrophysiological characterization of GPCR and ligand-gated channel cross-talk / Tak Pan Wong, Xian-Ming Yu and Yu Tian Wang -- 16. BRET as a strategy to evaluate receptor-receptor or receptor-protein interactions / Karin A. Eidne and Kevin D. G. Pfleger.

Owning institution

1. Columbia University Libraries

Bibliography (note)

1. Includes bibliographical references and index.