Research Catalog

Gene family targeted molecular design

Title
  1. Gene family targeted molecular design / edited by Karen E. Lackey.
Published by
  1. Hoboken, N.J. : John Wiley & Sons, [2009], ©2009.

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FormatTextAccessRequest in advanceCall numberRM301.3.G45 G457 2009Item locationOff-site

Details

Additional authors
  1. Lackey, Karen.
Description
  1. xvi, 347 pages, 16 unnumbered pages of plates : illustrations (some color); 25 cm
Subject
  1. Pharmacogenetics > methods
  2. Models, Molecular
  3. Pharmacogenomics
  4. Ion Channels > genetics
  5. Drug Design
  6. Genes
  7. Drugs > Design
Contents
  1. Ch. 1. Drug Discovery by Gene Family / Karen Lackey -- Ch. 2. G-Protein Coupled Receptors / Stephen Garland and Tom Heightman -- Ch. 3. Ion Channels Gene Family: Strategies for Discovering Ion Channel Drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Ch. 4. Integrins / David D. Miller -- Ch. 5. Strategies for Discovering Kinase Inhibitors / Jerry Adams, Paul Bamborough, David Drewry and Lisa Shewchuk -- Ch. 6. Protease-Directed Drug Discovery / Richard Sedrani, Ulrich Hommel and Jorg Eder -- Ch. 7. Small Molecule Inhibitors of Protein-Protein Interactions: Challenges and Prospects / Adrian Whitty -- Ch. 8. Transporters / Anne Hersey, Frank E. Blaney and Sandeep Modi -- Ch. 9. Nuclear Receptors / Hiroyuki Kagechika and Aya Tanatani -- Ch. 10. Summary and Comparison of Molecules Designed to Modulate Druggable Targets in the Major Gene Families / Karen Lackey.
Owning institution
  1. Columbia University Libraries
Bibliography (note)
  1. Includes bibliographical references and index.