Research Catalog

Translational medicine : strategies and statistical methods

Title
  1. Translational medicine : strategies and statistical methods / edited by Dennis Cosmatos and Shein-Chung Chow.
Published by
  1. Boca Raton : Chapman & Hall/CRC, [2009], ©2009.
Supplementary content
  1. Publisher description

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Details

Additional authors
  1. Cosmatos, Dennis.
  2. Chow, Shein-Chung, 1955-
Description
  1. xiv, 224 pages, 4 unnumbered pages of plates : illustrations (some color); 25 cm.
Summary
  1. "The development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting treatments approved for marketing and to the patients are decreasing. As a result, translational medicine (TM) is becoming increasingly important in the healthcare industry - a means of transitioning from the initial lab discovery to the patient's bedside, with minimal disconnect. Translational Medicine: Strategies and Statistical Methods provides a comprehensive review of statistical design and methodology commonly employed in this bench-to-bedside research."--BOOK JACKET.
Series statement
  1. Chapman & Hall/CRC biostatistics series ; 28
Uniform title
  1. Chapman & Hall/CRC biostatistics series ; 28.
Subject
  1. Medical innovations
  2. Medicine > Statistical methods
  3. Biochemical markers
  4. Drug development
  5. Drug Evaluation
  6. Biomarkers, Pharmacological
  7. Biomedical Research > trends
  8. Diffusion of Innovation
  9. Drug Design
  10. Models, Statistical
Contents
  1. 1. Translational Medicine: Strategies and Statistical Methods / Dennis Cosmatos and Shein-Chung Chow -- 2. Strategic Concepts in Translational Medicine / Dennis Cosmatos, Giora Feuerstein and Shein-Chung Chow -- 3. Design and Analysis Approaches for Discovery Translational Medicine / Dennis Cosmatos, Shein-Chung Chow, Stephen B. Forlow, Jennifer A. Isler, Zhaosheng Lin, Michael E. Burczynski, Jessie Q. Xia and S. Stanley Young -- 4. Biomarker Development / Mark Chang -- 5. Targeted Clinical Trials / Jen-pei Liu -- 6. Statistical Methods in Translational Medicine / Shein-Chung Chow, Siu-Keung Tse and Dennis Cosmatos -- 7. Nonparametric Methods in Translational Research / Kongming Wang and Shein-Chung Chow -- 8. Model Selection/Validation / Jen-pei Liu -- 9. Translation in Clinical Information between Populations - Bridging Studies / Chin-Fu Hsiao, Mey Wang, Herng-Der Chern and Jen-pei Liu -- 10. Translation in Clinical Technology - Traditional Chinese Medicine / Chin-Fu Hsiao, Hsiao-Hui Tsou and Shein-Chung Chow.
Owning institution
  1. Columbia University Libraries
Bibliography (note)
  1. Includes bibliographical references and index.