Probability models for DNA sequence evolution
- Title
- Probability models for DNA sequence evolution / Rick Durrett.
- Published by
- New York : Springer, ©2002.
- Author
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Status | Format | Access | Call number | Item location |
---|---|---|---|---|
Status | FormatText | AccessUse in library | Call numberQH438.4.S73 D87 2002 | Item locationOff-site |
Details
- Description
- viii, 240 pages : illustrations; 24 cm.
- Summary
- Many researchers in statistics, biology, mathematics, and computer science are working in the area of genetics. This book presents mathematical techniques for understanding sequence evolution. Throughout the book, the theory is developed in close connection with data from more than 60 experimental studies from the biology literature that illustrate the use of these results. This book is written for mathematicians and for biologists alike. It assumes no previous knowledge of concepts from biology and only a basic knowledge of probability.
- Series statement
- Probability and its applications
- Uniform title
- Probability and its applications (Springer-Verlag)
- Subject
- Genetics > Statistical methods
- Nucleotide sequence > Statistical methods
- Probabilities
- Evolutionary genetics > Statistical methods
- Variation (Biology) > Statistical methods
- Molecular evolution
- Evolution, Molecular
- Models, Genetic
- Base Sequence
- Probability
- probability
- Molecular evolution
- Evolutionary genetics > Statistical methods
- Genetics > Statistical methods
- Nucleotide sequence > Statistical methods
- Probabilities
- Variation (Biology) > Statistical methods
- DNS-Sequenz
- Evolution
- Stochastisches Modell
- Genanalyse
- Waarschijnlijkheidstheorie
- Modellen
- Evolutietheorie
- Contents
- 1. Basic Models. 1.1. The ATGCs of Life. 1.2. Wright-Fisher Model and the Coalescent. 1.3. Ewens Sampling Formula. 1.4. Infinite Sites Model. 1.5. Finite Sites, Four Nucleotides -- 2. Neutral Complications. 2.1. Nonconstant Population Size. 2.2. Recombination. 2.3. Population Subdivision. 2.4. Spatial Structure: Stepping Stone Model -- 3. Natural Selection. 3.1. Directional Selection. 3.2. Balancing Selection. 3.3. Background Selection. 3.4. Hitchhiking -- 4. Statistical Tests. 4.1. Tajima's D Statistic. 4.2. Fu and Li's D. 4.3. The HKA Test. 4.4. MacDonald-Kreitman -- 5. Genome Rearrangement. 5.1. Chromosome Size. 5.2. Inversions. 5.3. Translocations. 5.4. Genome Duplication.
- Owning institution
- Princeton University Library
- Bibliography (note)
- Includes bibliographical references (p. [223]-237) and index.