Research Catalog

Details

Additional authors

1. Beddell, C. R.

Description

1. xiv, 287 pages : illustrations (some color); 24 cm

Summary

1. This text, examining the design of drugs to macromolecular targets, covers such topics as receptor fit technology; drug interactions with target enzymes of known structures; computer modelling of drug-DNA intercalative compounds; and perspectives in medicinal chemistry.

Subject

1. Drugs > Design
2. Macromolecules
3. Molecular recognition
4. Drug Design
5. Macromolecular Substances
6. Arzneimitteldesign
7. Arzneimittelentwicklung
8. Arzneistoffträger
9. Biomolekül
10. Makromolekül
11. Molekulare Erkennung
12. Molekülstruktur
13. Wechselwirkung
14. Aufsatzsammlung
15. Arzneimitteldesign
16. Aufsatzsammlung
17. Molekulare Erkennung
18. Arzneimittelentwicklung
19. Wechselwirkung

Contents

1. The Role of macromolecules in drug action / G.R. Marshall -- Ligand fitting methodology / A.S. Gilbert and J.N. Champness -- Compounds designed to bind to haemoglobin / R. Wootton -- Drug interactions with target enzymes of known structure / B. Roth and D.K. Stammers -- Multiple modes of binding of thyroid hormones and other iodothyronines to human plasma transthyretin / P. de la Paz [and others] -- Computer modelling of drug-DNA intercalative interactions / S. Neidle -- Crystallographic investigations of glycolytic enzymes from trypanasoma brucei: potential starting points for the design of new sleeping sickness drugs / W.G.J. Hol and R.K. Wierenga -- Drug discovery and invention: some approaches compared / A.S. Gilbert and R.M. Hyde.

Owning institution

1. Princeton University Library

Bibliography (note)

1. Includes bibliographical references and indexes.