The Search for antiviral drugs : case histories from concept to clinic

Title
  1. The Search for antiviral drugs : case histories from concept to clinic / Julian Adams, Vincent J. Merluzzi, editors.
Published by
  1. Boston : Birkhäuser, ©1993.

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StatusFormatTextAccessUse in libraryCall numberRM411 .S39 1993Item locationOff-site

Details

Additional authors
  1. Adams, Julian, 1954-
  2. Merluzzi, Vincent J., 1949-
Description
  1. xii, 240 pages : illustrations; 24 cm
Subject
  1. Antiviral agents
  2. Nucleosides > Derivatives > Therapeutic use
  3. HIV infections > Chemotherapy
  4. Antiviral Agents
  5. Nucleosides > therapeutic use
  6. HIV Infections > drug therapy
  7. Geschichte
  8. HIV-Infektion
  9. Virostatikum
  10. Aufsatzsammlung
  11. Virusziekten
  12. Geneesmiddelen
  13. Anti-inflamatorios (farmacologia)
Contents
  1. Introduction : the first effective antiviral / Herbert E. Kaufman -- Discovery and development of zidovudine as the cornerstone of therapy to control human immunodeficiency virus infection / Kathryn H. Pattishall -- Discovery of nevirapine, a nonnucleoside inhibitor of HIV-1 reverse transcriptase / Julian Adams and Vincent J. Merluzzi -- Discovery of TIBO, a new family of HIV-1-specific reverse transcriptase inhibitors / Rudi Pauwels -- Discovery and development of 2-pyridinone HIV-1 reverse transcriptase inhibitors / Mark E. Goldman -- Discovery and development of the HIV proteinase inhibitor Ro 31-8959 / Noel A. Roberts and Sally Redshaw -- A new approach to antiviral chemotherapy : intervention in viral gene expression by HIV tat antagonists / Ming-Chu Hsu and Steve Tam -- Discovery of pirodavir, a broad-spectrum inhibitor of rhinoviruses / Koen Andries -- sICAM-1 as a receptor antagonist for rhinoviruses : a model system of adhesion molecules as cell receptors for viruses / Steven D. Marlin.
  2. (Cont.) Inactivation of herpes simplex virus ribonucleotide reductase by subunit association inhibitors : a potential antiviral strategy / Michel Liuzzi and Robert Déziel.
Owning institution
  1. Princeton University Library
Bibliography (note)
  1. Includes bibliographical references and index.